Study says a gene inhibits HIV replication

Study says a gene inhibits HIV replication

A recent study in the UK found that there is a gene that can help suppress the spread of HIV in the body. Researchers believe that in the future, new AIDS therapies with fewer side effects can be developed accordingly.

Researchers from King ’s College, University of London, UK, and other institutions reported in a new issue of Nature that they introduced human immunodeficiency virus type 1 (HIV-1), which can cause AIDS, into two different human cell lines, including The expression of MX2 gene in a cell line is "turned on", that is, the gene can fully function, and the expression of this gene in the control group is "turned off".

The experimental results show that in cell lines with suppressed MX2 gene expression, the virus can continue to replicate and spread, while in cell lines with full expression of this gene, the virus loses the ability to replicate and new viruses are no longer produced.

The researchers said that there was not much research on the MX2 gene, and this study found that this gene has strong anti-viral ability and can inhibit the replication and spread of HIV-1.

Professor Mike Malim, who participated in the research, said that this study further explores the "interaction" mechanism between the HIV-1 virus and the human immune system, which will help the future treatment of AIDS by activating the antiviral function of the immune system The autoimmune system to prevent and cure diseases is often the least toxic and side effects.

Study says a gene inhibits HIV replication

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