The application of thermal analysis in the pharmaceutical and food industry-the third round of the prize survey activity is looking forward to your joining!

Adhering to the enterprise tenet of "Quality First, Courage to Create and Pursue Change", the METTLER TOLEDO Group has always been committed to providing global customers with excellent quality precision instruments and weighing instruments and comprehensive and detailed technical support services. -Toledo Thermal Analysis Awarded Survey Activity ", on the one hand, it investigates the thermal analysis users' understanding and purchase of METTLER TOLEDO thermal analyzers, and on the other hand, it is to allow users to enjoy a better product experience.

As long as you complete and respond to the questionnaire completely and effectively before August 10, 2012, you will have a chance to get a Swiss army knife! The opportunity is not lost! Customers are welcome to participate actively!

Having experienced the heavy blow of the melamine incident, the haze of the Clenbuterol incident, and the clamor of the plasticizer incident, to the recent poison capsule incident, food and drug safety issues have become lingering nightmares in Chinese hearts. How to buy products with confidence has become an urgent issue for consumers.

Heat (ie temperature) is one of the main controlling factors used in food processing. DSC can characterize these processes (such as boiling or freezing), and can determine other physical or chemical properties (such as the composition of the swelling packaging film of starch) by means of temperature programs. In short, thermal analysis, with its fast and effective detection method, can determine the composition of food and speculate on the freshness and shelf life of the food. This is not bad news for consumers to buy food with confidence.

In the pharmaceutical field, the study of polymorphism and pseudopolymorphism is an important field of thermal analysis applications. Many drug substances exist in several crystal forms, which have an important effect on solubility and bioavailability. Thermal analysis can use its high-speed detection methods to achieve drug melting point determination, purity determination, stability testing, substance characterization and identification, research on the interaction between active ingredients and inactive ingredients, phase diagram determination, glass transition measurement of amorphous substances And polymorphic observations. This is also a great benefit for consumers to buy medicines at ease.

Case Application Case

1. Sample preparation of butyl hydroxyanisole

Different sample preparation (especially mechanical treatment) may lead to different measurement results. This is especially true for substances that are polymorphic ...

2. Annealed butyl hydroxyanisole polymorph

Inappropriate storage conditions or process conditions of the substance can cause the crystal form to change, especially when the transition temperature is close to the storage or processing temperature ...

3. TGA of sugar and starch

TGA can measure moisture content, active ingredient content and ash content. In addition, the melting point and TGA inflection temperature on the simultaneous DTA curve can be used to identify different carbohydrates ...

The first two issues of "Mettler-Toledo Thermal Analysis in Pharmaceuticals and Food-Awarded Survey Activities" have received widespread attention and enthusiastic praise from consumers. Through the first two surveys, we have a better understanding of what thermal analysis users want. In order to better serve our customers, the third round of the award-winning survey campaign hits heavily, and we look forward to your participation!

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